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论文 甲状腺素与充血性心力衰竭 教育 |
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者常伴有正常甲状腺功能的病态综合征(ESS),而且T3与心衰程度相关,T3/rT3比率是其发病和死亡的独立危险因子[10]。既然T3有正性肌力作用,还能降低外周血管阻力,故甲状腺激素治疗能改善心衰患者的血液动力学障碍。但在临床中应将甲状腺激素能否作为治疗心衰的常规用药,其效果及副作用方面的评价等还有待于进一步研究。参考文献1WartofskyI,BurmanKD.Alterationsinthyroidfunctioninpatientswithsystemicillness.The“euthyroidsicksyndrom”.EndocrRev,1982,3:164.2PolicarR,BurgerAG,ScherrerU,etal.Thethyroidandheart.Circulaˉtion,1993,87:1435.3KleinI,OjamaaK,PowellS.Potentialclinicalapplicationsforparenteralthyroidhormonetherapy.HospForm,1993,28:848.4KlempererJD,ZelanoJ,HelmR,etal.Triiodothyromineimprovesleftventricularfunctionwithoutoxygenwastingeffectsfollowingglobalhyˉpothermicischemia.JThoracCardiovascSurg,1995,109:457.5BartalenaL,BarogioniS,GrassoL,etal.Interleukin-6andthethyˉroid.EurJClinEndocrinol,1995,132:386.6LjamasK,SamarclA,KupferJ,etal.Thyroidhormoneeffectsoncardiacgeneexpressionindependentofcardiacgrowthandproteinsynthesis.AmJPhysios,1992,263:534.7DykeCM,YehTJr,LehmanJD,etal.Triodothyromineenhancedleftventricularfunctionafterischemicinjury.AnnThoracSurg,1991,52:14.8KlempererJD,ZelanoJ,HelmR,etal.TriodothyromineimprovesleftventricularfunctionwithoutoKxygenwastingeffectfollowingglobalhyˉpothermicischemia.JThoracCardiovacsSurg,1995,109:457.9KleinI,OjamaaK.Thyroidhormoneandbloodpressureregulation,inLaraghJH,BrennerBM(eds):Hypertension:Pathophysiology,Diagnoˉsis,andTreatment(ed2).NewYork:NY,Ravea,1994,2247.10HamiltonMA,StevensonLW,LuuM,etal.Alteredthyroidhormonemetabolisminadvancedheartfailure.JAmCollCardiol,1990,16:91.作者单位:028000内蒙古民族大学附属医院中华中西医杂志
上一页 [1] [2] 上一个偏方: 颅脑损伤后抗利尿激素分泌异常综合征20例临床分析 下一个偏方: 颈髓损伤后抗利尿激素分泌异常综合征诊治分析
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