fective and the total effective rate was 955%;in the control group,8 patients were clinically cured,4 markedly effective,3 effective,5 ineffective and the total effective rate was 750%.The therapeutic effect in the treatment group was superior to that in the control group (P＜005).Serum IL2 level was increased,and sIL2R decreased in the two groups after treatment (P＜001 compared with those before treatment),and the above changes were obvious in the treatment group (P＜005).The protein expression of platelet Fas and FasL and PAIgG level was downregulated (P＜001 compared with that before treatment),and the effect was obvious in the treatment group (P＜005).T Lymphocyte subtype CD+4 percentage and CD+4/CD+8 ratio were increased,and CD+8 percentage was decreased in the two groups after treatment (P＜005 compared with those before treatment).ConclusionTherapy of dispelling wind can enhance the therapeutic effect of bloodcooling and kidneytonifying herbs for chronic idiopathic thrombocytopenic purpura. Key words: PURPURA,THROMBOCYTOPENIC/TCD therapy；DISPELLING WIND；COOLING BLOOD；TONIFYING KIDNEY
特发性血小板减少性紫癜（idiopathic thrombocytopenia purpura,ITP）是常见出血性疾病，目前被公认为是一种由于患者体内产生自身抗血小板抗体，致使血小板寿命缩短，破坏增多，数量减少为病理特征的自身免疫性疾病，属中医“血证”、“紫斑”、“肌衄”等范畴。我们在以补肾凉血法治疗慢性特发性血小板减少性紫癜（ＣＩＴＰ）取得良好疗效的基础上［１］，加用祛风法使疗效得到进一步提高，同时还观察了该法对ＣＩＴＰ一些相关免疫指标的影响，现将结果报道如下。
1资料与方法
11病例选择
本研究病例来源于２００３～２００６年广州市中医医院的住院和门诊病人。纳入标准：（１）符合１９８６年１２月中华血液学会全国血栓与止血学术会议修订的特发性血小板减少性紫癜诊断标准，急慢性分型标准参照《邓家栋临床血液学》［２］。（２）年龄大于８岁、小于６５岁的患者。排除标准：（１）急性特发性血小板减少性紫癜；（２）继发性血小板减少症；（３）合并其他心脑血管、肝肾等系统严重原发病；（４）不能配合按规定用药者。
12一般资料
观察病例共４２例。采用随机数字表法随机分为对照组和治疗组两组。治疗组２２例，男８例，女１４例；年龄８～６４岁，平均（３０9±１４３）岁；病程６～４０个月，平均（２１９±１０８）个月。对照组２０例，男７例，女１３例；年龄８～６０岁，平均（３２６±１２４）岁；病程７～３８个月，平均（２０３±９４）个月。两组患者的性别、年龄、病程经统计学处理，差异无显著性意义（Ｐ＞００５），具有可比性。
13治疗方法
所有纳入治疗的病人均停用激素和免疫抑制剂治疗。如部分病人原用药量较大，估计立即停用激素或免疫抑制剂等药后可能出现病情
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