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甲基强的松龙冲击法治疗急性脊髓损伤的近期观察 |
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p;class of the American spinal cord injury institution，patients were graded the curative effect and relative complication of each patient were compared.Cases managing in 8 hours post injury were divided into methylprednisolone group，Cases managing beyond 8 hours post injury were divided into control group.Neurological functions were evaluated at admission，6 weeks and 6 months after injury.Results Sensation status increased significantly at 6 weeks and 6 months in experimental group(A group)，Motion status increased significantly at 6 months in experimental group(A group).Control group(B group) had no significant change of neurological function.Conclusion Methylprednisolone(MP) is an effective drug in treating acute spinal cord injury.Early proper application of MP can promote early neurolojical functions recovery.But MP have not lead to increasing incidence rate of complication during treatment.
Key words：spinal cord injury；methylprednisolone；neurological function；complication
急性脊髓损伤(acute spinal cord injury，ASCI)致残率和致死率较高，如何采取更有效措施降低脊髓继发性损害，减轻患者的痛苦，提高生活质量，是脊柱外科亟待解决的难题之一。在过去的25年里，基础和临床研究均证明大剂量甲基强的松龙(MP)对ASCI的恢复是有益的，甚至在一定程度上改变了人们对脊髓损伤悲观失望的观点［1］。
1 资料与方法
1.1 一般资料 2002年8月至2005年8上一页 [1] [2] [3] [4] [5] 下一页
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