尿毒清颗粒治疗早期糖尿病肾病的疗效观察

　　本观察显示，尿毒清颗粒治疗组2个月后UAER略有下降，低于非尿毒清颗粒治疗组(P<0.05);6个月后治疗组UAER仍保持下降趋势，非尿毒清颗粒治疗组UAER略有增高;2个月和6个月后尿毒清颗粒治疗组血TC和TG也较非尿毒清颗粒治疗组显著的下降(P<0.05);而内生肌酐清除率升高(P<0.05或0.01)。提示尿毒清颗粒能够有效地降低早期DN患者的UAER，调节脂质代谢紊乱，改善肾功能。观察还表明，随治疗时间延长，尿毒清颗粒治疗组较非尿毒清颗粒治疗组各项观测指标持续好转，提示尿毒清颗粒治疗早期DN长期用药效果更明显。

　　综上所述，尿毒清颗粒可通过通腑降浊、健脾利湿、活血化瘀的功效，抑制DN患者AGEs、调节脂质代谢紊乱、减少蛋白尿等多个途径的作用，改善肾功能，减少并发症，延缓DN的病程进展，长期服用效果更好。

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