Ca2+activity of sarcoplasmic reticulum reduce, especially mitochondria, so it can improve diastolic dysfunction.
Our clinical observation had proved that intravenous therapy with CP can significantly increase clinical (96.2% vs. 57.1%),E/A (81.65% vs. 10.34%), Ea/Aa (83.49% vs. 13.79%) and E/Ea (92.86% vs. 12.00%) effects, P<0.01 all, compared with routine treatment group,therefore, a better life quality will provided to the patients. Thereby creatine phosphate sodium has invaluable clinical significance in preventing and treating myocardium diastolic dysfunction
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