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磷酸肌酸对早期舒张功能障碍的疗效

Ca2+activity of sarcoplasmic reticulum reduce, especially mitochondria, so it can improve diastolic dysfunction.

  Our clinical observation had proved that intravenous therapy with CP can significantly increase clinical (96.2% vs. 57.1%),E/A (81.65% vs. 10.34%), Ea/Aa (83.49% vs. 13.79%) and E/Ea (92.86% vs. 12.00%) effects, P<0.01 all, compared with routine treatment group,therefore, a better life quality will provided to the patients. Thereby creatine phosphate sodium has invaluable clinical significance in preventing and treating myocardium diastolic dysfunction

  【参考文献】

  \[1\] 郭继鸿.舒张性心衰的新理念.北京:人民卫生出版社,2009:10.

  [2]李佳蓓,黄岚,祝善俊. 心力衰竭时心肌能量代谢的研究进展. 心血管康复医学杂志, 2009, 18(1):85.

  [3]Hearse DJ, Stewart DA , Braimbridge MV,et al. Cellular protection during myocardial ischemia: the development and characterization of a procedure for the induction of reversible ischemic Circulation, Vol 54, 193-202.

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  [11]Pedone V. As assessment of the activity of creatine phosphate (Neoton) on premature ventricular beats by continuous ECG monitoring in patients with coronary cardiac disease. Clinical Trials J,1984, 21:91.

  

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