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脑电图双频谱指数预测七氟醚麻醉病人切皮体动反应的临床评价 |
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张德林 郭曲练 陈先来 张建国 王艳青 谭秀娟
摘要 目的:用预测概率(PK)评价七氟醚吸入麻醉时脑电图双频谱指数(BI)预测病人对切皮刺激体动反应的准确性。方法:选择行上腹部择期手术的成年患者29例,麻醉诱导用异丙酚及七氟醚,浓度随机为0.6MAC、1.0MAC、1.5MAC或2.0MAC的七氟醚维持15分钟以上切皮,观察病人的体动反应。取HR、MAP、SABP、BI及95%SEF等指标的切皮前1分钟数据,用于计算PK。结果:MAC与BI预测概率显著高于0.5;95%SEF、SABP及MAP的预测概率稍低,但与0.5比较统计学上差别显著,其中95%SEF的PK值与BI及MAC的PK值比较差别显著;心率的PK值接近0.5。结论:BI、SABP、MAP及95%SEF对七氟醚麻醉病人的切皮体动反应均有较好预测作用,但BI更敏感。 关键词 预测概率 七氟醚 脑电图 双频指数 麻醉深度
The clinical evaluation of the bispectral index of electroencephalogram in predicting movement during skin incision in patients under sevoflurane anesthesia Zhang Delin,Guo Qulian,Chen Xianlai,et al.Department of Anesthesiology,Fujian Medical University,Fuzhou 350001 Abstract Objective:To evaluate the efficacy of the bispectral index (BI) in predicting patient movement on skin incision under sevoflurane anesthesia with the PK statistic.Method:Twenty-nine adult patients,scheduled for elective upper abdominal surgery,were selected.Anesthesia was induced with propofol and 4%-5% sevoflurane in oxygen and maintained with one of four randomized sevoflurane concentrations(0.6MAC,1.0MAC,1.5MAC and 2.0MAC) for fifteen minutes,then skin incision was performed by the surgeon at the planned site of the surgery,and each patient was observed carefully about 2 minutes to detect purposeful movement.The data of BI,95%SEF,MAP,SABP and HR in one minute before skin incision were applied to statistically analysis .Result:The PK was significantly greater than 0.5 for the sevoflurane level and the BI.The PK of 95%SEF,SABP and MAP were less than that of the level of sevoflu or BI,but was significantly greater than 0.5 The PK of HR was close to 0.5.Conclusion:These indicators of B,BP and 95%SEF may predict patient movement to skin incision under sevoflurane anesthesia,of which the BI is the most sensitive. Key words Prediction probability Electroencephalogram Sevoflurane Bispectral index Depth of anesthesia
随着电子计算机的发展,90年代初脑电图双频[1] [2] 下一页 上一个医学论文: 全麻下经胸食管癌切除前后病人外周血TNF T淋巴细胞及其亚群的改变 下一个医学论文: 异丙酚麻醉诱导对体循环和肺循环的影响
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