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异丙酚伍用不同剂量芬太尼用于人工流产手术麻醉 |
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侯炯 程文华 许涛 徐美英 邓小明
摘要 目的：研究异丙酚联合应用不同剂量的芬太尼在人工流产手术的麻醉作用。方法：ASAⅠ～Ⅱ级人工流产患者64例，随机分为三组，A组22例为对照组，B组22例，C组20例。A组静注异丙酚2mg／kg，B组静注异丙酚2mg／kg及1μg／kg芬太尼，C组静注异丙酚2mg／kg及2μg／kg芬太尼。异丙酚均于45～60秒缓慢注入。观察三组患者诱导及苏醒时间、异丙酚用量及呼吸抑制情况。结果：麻醉诱导时间B、C两组少于A组（P＜0.01），苏醒时间B组少于A组（P＜0.05）。异丙酚用量B、C两组均少于A组（P＜0.01）。呼吸抑制发生率A组45％、B组50％、C组85％，A、B两组的发生率接近，无显著性差异，但两组均与C组相差显著（P＜0.01，P＜0.05）。而呼吸抑制的平均时间B组为最短。结论：异丙酚联合应用芬太尼用于人工流产手术麻醉可加强镇痛，减少异丙酚用量。异丙酚联合应用1μg／kg芬太尼，是一种较为安全有效的配伍方法。
关键词 人工流产 异丙酚 芬太尼
Propofol with Different Dosage of Fentanyl for Induced Abortion Anesthesia
Hou Jiong，Cheng Wenhua，Xu Tao
(Department of Anesthesiology,Changhai Hospital,Second Military Medical Universty,Shanghai 200433)
Abstract Objective：To explore the effect of propofol anesthesia with different dosage of fentanyl in induced abortion．Methods：Sixty-four induced abortion patients were randomly divided into three groups：group A （control group） 22 patients，group B 22 patients and group C 20 patients．Group A was administrated propofol 2mg／kg only；group B was administrated propofol 2mg／kg with 1μg／kg fentanyl；group C was 2mg／kg propofol with 2μg／kg fentanyl．Induction time，recovery time，the dosage of propofol and respiration depression were recorded．Results：Propofol dosage in group B and C was less than that in group A （P＜0.05）．Respiration depression occurrence of group A，B and C was 45％，50％ and 85％ respectively．Conclusion：Propofol with fentanyl for induced abortion anesthesia may enhance analgesia and reduce the propofol dosage．Propofol with 1μg／kg fentanyl is a safe and effective protocol for induced abortion anesthesia．
Key words Induced abortion Propofol Fentanyl
异丙酚由于起效快、苏醒快、麻醉后不影响患者的时空定向力，被广泛用于门诊手术。但异丙酚镇痛作用微弱。本文通过应用不同剂量的芬太尼辅助异丙酚用于人工流产手术麻醉探讨合理的麻醉方法。
资料与方法
选择自愿接受异丙酚麻醉的人工流产患者64例，ASAⅠ～Ⅱ级，无药物过敏史。将患者随机分为三组，A组为对照组22例，给予异丙酚2mg／kg；B组22例，给异丙酚2mg／kg＋芬太尼1μg／kg；C组20例，给异丙酚2mg／kg＋芬太尼2μg／kg。患者入室后开放[1] [2] 下一页
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