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非淋菌性尿道炎233例病原体及支原体药敏分析

【摘要】 目的  探讨非淋菌性尿道炎(NGU)病原体和耐药情况。 方法  应用培养和衣原体抗原快速免疫测定法对NGU患者的尿道(宫颈)分泌物进行检测,同时测定支原体对12种抗生素的耐药情况。 结果  233例NGU患者共培养出371株菌种,其中Uu、Mh、Ct、Cd、细菌比例分别为52.56%、23.99%,14.29%、2.96%和6.20%;混合感染率达到44.74%,Uu与Mh混合感染率分别达到20.21%;3种或以上病原体感染率达4.58%。 结论  NGU患者病原体以支原体为主,但混合感染情况增多,而且支原体的耐药情况较为严重,给临床治疗带来困难。
    
  关键词  非淋菌性尿道炎 病原体 支原体 药敏试验
    
  Etiological examination and mycoplasma drug sensitive analysis of233 patients with nongonococcal urethritis
     
  Li Zhen,Qian Zhenyun
    
  Department of Dermatology,Longgang People s Hospital,Shenzhen518172.
   
  【Abstract】 Objective To study etiological examination and mycoplasma resistant against antibiotics of the pa-tients with nongonococcal urethritis.Methods Urethral(or cervical)samples of the patients with nongonococcal urethri-tis were examined by c-c rapid assay and culture,drug sensitive analysis of12antibiotics against mycoplasma were done at the same time.Results The result showed that806positive specimens were isolated from531patients with nongono-coccal urethritis,the positive rates of U.urealyticum(Uu),M.hominis(Mh),C.trachomatis(Ct),Candidia(Cd)and bacteria were52.56%,23.99%,14.29%,2.96%,6.20%respectively;44.74%were mixed infection,20.21%were positive for Uu+Mh,and4.58%for three or more etiologies.Conclusion Then mycoplasma was the main etiologies of the patients with NGU,but mixed infections and mycoplasma resistant against antibiotics were more,which will make dif-ficult to deal with NGU clinically.
   
  Key words nongonococcal urethritis etiology mycoplasma drug sensitive test
     
  近年来,非淋菌性尿道炎(non-gonococcal ure-thritis,NGU)的发病率增多,已成为最常见的性传播疾病之一。为了解NGU的病原体及其药敏程度,我科于2003年4月~2004年10月对233例NGU患者进行沙眼衣原体(C.trachomatis,Ct)、解脲支原体(U.urealyticum,Uu)、人型支原体(M.hominis,Mh)、念珠菌(Ca

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