水平上调胰腺癌细胞中MMP2、MMP9和VEGF的表达，从而进一步促进胰腺癌细胞发生远处侵袭转移。总之，对肿瘤细胞微环境中信号物质的研究对于明确肿瘤发生远处侵袭转移机制具有重要意义，在这一领域仍然需要进行深入的研究。
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