【摘要】 目的 观察甘乐联合丹参治疗慢性乙型肝炎(CHB) 的疗效。方法 将120 例慢性乙型肝炎患者治疗组60 例，给予甘乐注射液80 mg加入5%葡萄糖注射液250 mL中静脉滴注，丹参注射液20 mL 加入5%葡萄糖注射液250 mL 静脉滴注，均1 次/d;对照组60 例，给予甘乐注射液，剂量、疗法同治疗组，两组药物在治疗20 天后改为口服,疗程均为6 月。治疗结束后观察两组症状改善情况及肝脏功能生化指标的变化。结果 两组治疗后症状均有明显改善，肝脏功能生化指标和肝纤维化指标均有明显好转，治疗组肝功能指标和肝纤维化指标变化更优于对照组(P分别<0.05和0.01 )。结论 甘乐联合丹参可明显改善肝炎病人症状及肝功能，并且抗纤维化效果确切。
【关键词】 慢性乙型肝炎;丹参;甘乐
Clinical Observation of Compound Diisopropylamine Dichloroacetate Combined
with Salviae Miltiorrhizae in Treating Chronic Hepatitis BJIANG Yuanming, ZHAO Chuan,TANG Kunlun
(Suining Center Hospital, Suining 629000 China)Abstract： Objective To observe the clinic effects of diisopropylamine dichloroacetate and salviae miltiorrhizae on chronic hepatitis B (CHB). Methods 120 patients，who suffer from CHB，were divided into two groups randomly. The treatment group (60 cases) were given compound diisopropylamine dichloroacetate (80 mg/day) combined with salviae miltiorrhizae composita (20 mL/day), and control group (60 cases) were only given compound diisopropylamine dichloroacetate (80mg/day). Both these 2 groups took medicine after 20 days drugs treatment, and the course would last for 6 months. The symptoms, the hepatic functions and the hepatic fibrosis index at the beginning, ending of the treatment were observed. Results After treatment, the patients symptoms, sign and index of liver function and hepatic fibrosis were significantly improved. And the parameters of liver function and hepatic fibrosis in treatment group were obviously better than that of control group at the ending the treatment. Conclusion Compound diisopropylamine dichloroacetate combined with salvia mihiorrhiza could obviously improve symptoms, sign and index of liver function and hepatic fibrosis in chronic hepatitis B patients.
Key words：chronic hepatitis B(CHB);compound diisopropylamine dichloroacetate;salviae miltiorrhizae
慢性乙型肝炎(chronic hepatitis B，CHB)在我国发病率高，目前临床还缺乏可靠的特效治疗药物。
[1] [2] [3] 下一页
您现在的位置： 绿色健康网 >> 医学论文 >> 外科论文 >> 正文