后的免疫治疗,在间质性膀胱炎的治疗中尚未见报道,而舍尼亭为竞争性 M 胆碱受体阻滞剂,可急迫性尿失禁症状。本研究膀胱扩张后口服环磷酰胺和舍尼亭,临床症状得到明显改善,因而支持IC为一种自身免疫性疾病。外科手术治疗术式很多,诸如经尿道溃疡电切术、经尿道溃疡激光切除术、膀胱部分切除术、膀胱扩大成形术以及尿道流改术等[8],但外科手术治疗应在所有保守治疗失败后不得已才采取的治疗方法。
【参考文献】
1 Gillenwater JY, Wein AJ. Summary of the national institute of arthritis, diabetes, digestive and kidney diseases workshop on Interstitial cystitis, national institutes of health, Bethesda, Maryland, August 28-29, 1987.J Urol, 1988,140(1):203~206.
2 Parsons M, Toozs-Hobson P. The investigation and management of interstitial cystitis. J Br Menopause Soc, 2005,11(4):132~139.
3 Nigro DA,Wein AJ,Foy M,et al. Associations among cystoscopic and urodynamic findings for women enrolled in the Interstitial Cystitis Data Base (ICDB) Study.Urology, 1997,49(5A Suppl):86~92.
4 何学文.间质性膀胱炎诊治研究进展.国外医学·泌尿系统分册,2003 增刊:25~28.
5 Ruiz JL,Alonso M,Moreno B,et al. Dimethyl sulfoxide in the treatment of interstitial cystitis Actas Urol Esp. 1991,Jul-Aug;15(4):357~360.
6 Hanno PM, Wein AJ. Conservative therapy of interstitial cystitis.Semin Urol,1991,9(2):143~147.
7 Elbadawi A. Interstitial cystitis: a critique of current concepts with a new proposal for pathologic diagnosis and pathogenesis.Urology, 1997,49(5A Suppl):14~40.
8 Parsons M, Toozs-Hobson P. The investigation and management of interstitial cystitis. J Br Menopause Soc, 2005,11(4):132~139.
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