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非体外循环冠状动脉搭桥术在低射血分数病人中的应用

#e# [关键词] 冠状动脉搭桥术,非体外循环,左室功能低下,射血分数
  目的:总结分析25例射血分数小于30%的冠心病患者进行的非体外循环冠状动脉搭桥术。

  方法:2000年2月至2001年4月进行的选择性OPCAB手术25例,全部经左心室造影测定射血分数在6-30%之间,平均25.6±5.6%。合并心梗史19例,急性心肌梗塞后1个月内6例,不稳定心绞痛12例。心功能II级9例,III级12例,IV级4例。冠状动脉造影提示两支病变3例,三支病变22例,左主干7例。

  结果:全部病例均完成OPCAB手术,平均远端吻合口数目为3.9±0.8个,使用主动脉内球囊反搏14例,其中10例均在手术中安放。手术死亡1例,于术后2月死于多器官功能衰竭。有2例术后出现急性左心衰,安放主动脉内球囊反搏后保守治疗好转。其中2例为室颤,均复苏成功。

  结论:低射血分数患者实施OPCAB手术有良好的可行性和近期效果,而长期结果仍有待进一步观察。

  Off -Pump Coronary Artery Bypass Grafting

  in Patients with Low Ejection Fraction

  Wan Feng. Chen Yu, Wang Jingsheng, Wang Xinsheng, Chen Shenglong

  Abstract

  Objective: To analyze 25-case off-pump coronary artery bypass grafting (OPCAB) in patients with low left ventricular ejection fraction.

  Method:25 case selective off pump coronary artery bypass grafting from February of 2000 to April of 2001 were analyzed, whose mean left ventricular ejection fraction by ventricular angiography was 25.6±5.6%。There were 19 cases with history of myocardial infarction, 12 case with unstable angina pectoris, 22 cases with triple vessels defect and 7 cases with left main coronary defect.

  Results:OPCAB surgery were performed in all the cases. The mean number of distal anastamose was 3.9±0.8. Intra-aortic balloon pump was used in 14 cases, of which 10 cases were inserted balloon in operating room. There was 1 death due to multiple system and organ failure2 months after operation. 2 cases with acute heart failure and 2 cases with ventricular fibrillation after operation were successfully rescued.

  Conclusion:OPCAB had good feasibility and early outcome in patients with low ejection fraction. However, the long-term outcome will be observed.

  Key Words: coronary artery bypass, off pump, ejection fraction, left ventricular dysfunction

  严重左室功能低下被认为是冠状动脉搭桥手术的危险因素[2]。Benetti等[1]人成功开展的非体外循环冠状动脉搭桥术(OPCAB)避免或减少了体外循环损伤和缺血再灌注损伤,是现代微创冠脉外科的代表术式之一,对于低射血分数的病人将获益更

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