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60例肥胖儿童血糖 胰岛素与高血压的关系 |
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郭行平 李家宜 马广松
【摘要】 目的 了解儿童血糖、血胰岛素与高血压的关系。方法 对肥胖 儿童及正常对照儿童各60例进行空腹血糖(GS)、胰岛素(IS)及高密度脂蛋白(H DL)测定,其中各30例做葡萄糖耐量试验。结果 两组儿童空腹GS、HDL及糖负 荷后GS差异无显著性。肥胖组的空腹IS、糖负荷后IS、胰岛素曲线下面积及曲 线下面积的IS/GS均高于对照组,肥胖组有43例(71.7%)血压增高。结论 肥胖 儿童存在高胰岛素血症及胰岛素抵抗。肥胖与高血压关系密切。
【关键词】 肥胖症 血糖 胰岛素 高血压 Relationship between Blood Glucose, Insulin and Hypertension in 60 Obese Children Guo Xingping, Li Jiayi, Ma Guangsong. Capital Institute of Pediatrics, Beijing 100020
【Abstract】 Objective To study the relationship between blood glucose, insulin and hypertension in children. Methods Fasting serum glucose (GS), insulin (IS) and high-density lipoprotein (HDL) were determined in 60 obese children and 60 normal controls, and oral glucose tolerance test was performed for half of them. Results It showed that there were no significant differences in fasting GS, HDL and GS after glucose load between the two groups, and fasting IS, IS after glucose load, an area and a ratio of IS to GS under the insulin curve all were higher in the obese group than those in the control one. There were 43 obese children (71.7%) with hypertension. Conclusion There existed hyperinsulinemia and insulin resistance in obese children and there also was close relationship between obesity and hypertension in them.
【Key words】 Obesity Blood glucose Insulin Hypertension 随着生活水平的提高,肥胖儿童检出率增高。现已证明肥胖与高血压、糖尿 病互相关联,对健康威胁很大。我们对60例单纯肥胖和60例正常儿童进行血糖、 血胰岛素及高密度脂蛋白测定,其中各30例做了糖负荷试验,对肥胖儿检测血压, 探讨肥胖儿的血糖、血胰岛素、血脂和高血压的关系。
对象与方法
一、对象
肥胖组60例(男47例、女13例),年龄8~14岁,来自北京地区中小学生,经体 格及实验室检查(血、尿常规及肝、肾功能,部分做X线、心电图、超声心动图检 查)无异常者,体重指数(BMI)≥25[1]。
对照组60例(男41例、女19例),年龄与肥胖组相似,体格及实验室检查为健 康者,体重指数≤25。
二、方法
肥胖诊断:参照BMI指数:体重(kg)/身高2(m2),BMI指数≥25为肥胖。体重测 量应用RGT-140型体重计,身高测量用IG型身高坐高计。
[1] [2] 下一页 上一个医学论文: 石棉与烟雾溶液对人胚肺细胞DNA的损伤作用 下一个医学论文: 应用PCR方法检定单核细胞增多性李斯特菌
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