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纵向生命质量资料分析的Markov过程法及其应用 |
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万崇华 方积乾 周文清 秦学军
摘要:目的提出一种分析纵向生命质量资料的方法并探讨有关的应用问题。方法 基于Markov过程思想提出Markov过程法,并且用于212例吸毒者在戒毒期间生命质量的变化及影响因素分析。结果职业对状态1→2和状态2→3的转移强度系数分别为0.7912和0.6797;戒毒时间对状态1→2的转移强度系数为0.5663,戒毒方式对状态2→3的转移强度系数为0.2765。结论本文方法是一较好的纵向资料分析法,既能分析生命质量的状态转移又能分析转移的影响因素。职业、戒毒方式和戒毒时间能影响生命质量的变化。 关键词:Markov过程 纵向资料 生命质量 吸毒
Markov process method in analyzing longitudinal quality of life data
WAN Chonghua*, FANG Jiqian, ZHOU Wenqing,et al.
Department of Health Statistics, Kunming Medical College, Kunming 650031
Abstract:Objective To present a method to analyze longitudinal quality of life data and discuss some relevant questions. Method Based on the theories of Markov process, the Markov method was presented and used to analyze the change of quality of life status for 212 cases being detoxificated drug addicts and their influence factors. Results The intensity coefficients of status transient for 1→2 and 2→3 for occupation were 0.7912 and 0.6797 respectively; the coefficients for status 1→2 for the detoxification time was 0.5663 and that for 2→3 for the detoxification method was 0.2765. Conclusions The Markov method is good to analyze longitudinal quality of life data for it can analyze both the transient probabilities between any two status of quality of life and their influence factors. The results showed that the occupation of drug addicts, the detoxification time and method can affect the change of quality of life. Key words:Markov process Longitudinal data Quality of life Drug addiction
随着生命质量(quality of life,QOL)研究的兴起,涌现了大量的生命质量资料。鉴于生命质量资料的复杂性,一些学者[1~3]对其统计分析方法进行了专门的研究讨论。由于生命质量的时间依赖性,纵向的重复多次的生命质量测评才真正体现生命质量研究的精髓。但纵向资料的处理即使在其它领域也尚未很好解决,在生命质量领域更是鲜为人知。由此严重阻碍了生命质量测评的开展及深入,以致于目前多数仅开展横切面的测定或者前后两次的测定。 如果将生命质量在时间上的变化视为Markov过程,即可试用Markov过程思想来处理。实际上,已有一些研究者[1,2]注意到了这一点,但具体方法尚未见报道。为此,笔者应用Markov过程思想提出一种分析方法,并应用于吸毒者生命质量资料的分析。 方法及原理 由于生命质量的变化与时间[1] [2] 下一页 上一个医学论文: 神经酰胺介导粒细胞凋亡机理初探 下一个医学论文: 育龄妇女贫血状况调查及影响因素分析
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