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浅表淋巴结肿大的151例艾滋病患者淋巴结病理学分析 |
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卢祥婵 邓建宁 黄爱春 李雪琴 牟敏红 欧汝志 黄磊 赵敏
摘 要：目的 探讨浅表淋巴结肿大的HIV/AIDS患者的淋巴结病理类型及其特点.方法 取浅表淋巴结肿大的151例HIV/AIDS患者的淋巴结组织进行病理学检查,通过HE、抗酸、过碘酸雪夫和淀粉酶消化后过碘酸雪夫染色,光学显微镜下观察,描述和分析其病理结果及其与CD4+T淋巴细胞计数的关系.数据行卡方检验.结果 在151例HIV/AIDS患者的淋巴结病理结果中,表现为良性病变的有145例,占96.0%,表现为恶性肿瘤的有6例,占4.0%,其中结核病72例,淋巴结反应性增生34例,淋巴真菌感染23例(其中青霉病19例),AIDS相关淋巴结病14例,非霍奇金淋巴瘤5例,良性纤维组织细胞病1例,结核伴发真菌感染1例,间叶性恶性肿瘤1例.在所有患者中,CD4+T淋巴细胞计数<100×106/L的有83例,占55.0%.青霉病随着CD4+T淋巴细胞计数的减少,发病率明显升高(x2=7.757,P=0.021).结论 HIV/AIDS患者浅表淋巴结肿大的原因大多数为感染性疾病,主要为结核病及真菌感染,且多数发生在CD4+T淋巴细胞计数低下的患者,最常见的恶性肿瘤为非霍奇金淋巴瘤.
关键词：HIV感染;获得性免疫缺陷综合征;淋巴系统疾病;结核;真菌病
Analysis of the pathology of lymph nodes in 151 acquired immune deficiency syndrome patients with superficial lymphadenectasis
LU Xiang-chan（Department of Infectious Diseases,Forth People's Hospital of Nanning,Nanning 530023,China） DENG Jian-ning（Department of Infectious Diseases,Forth People's Hospital of Nanning,Nanning 530023,China） HUANG Ai-chun（Department of Infectious Diseases,Forth People's Hospital of Nanning,Nanning 530023,China） LI Xue-qin（Department of Infectious Diseases,Forth People's Hospital of Nanning,Nanning 530023,China） MOU Min-hong OU Ru-zhi HUANG Lei ZHAO Min
Abstract：Objective To investigate the pathological types and features of lymph nodes in human immunodeficiency virus(HIV)/acquired immune deficiency syndrome(AIDS)patients with superficial lymphadenectasis.Methods The tissues of lymph nodes were obtained from 151 HIV/AIDS patients with superficial lymphadenectasis for pathological examination.The pathological results were observed by light microscope after Hematoxylin-Eosin(HE),acid-fast,periodic acid-Schiff (PAS),and digested-PAS(D-PAS)staining.The pathological results of lymph nodes were described and the correlation between pathological changes and CD4+T lymphocyte count was analyzed.Chisquare test was used for the statistic analysis.Results The benign lesions were found in 145 patients (96.[1] [2] [3] 下一页
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