观察15~20年,无需增大剂量,长期应用无异动症、开关现象等副作用。对于因长期肌张力障碍所致的脊柱、足部畸形,可采用器械康复、功能锻炼等综合性方法帮助恢复。 本病较罕见,据估计,日本和英国DRD的发病率为1/200万,但迄今为止,国内仅报道过1个家系,可能与对本病不熟悉有关,本组除1例外,误诊时间均较长,治疗前平均病程达12.3年。由于本病有特效治疗方法,如能早期诊断、早期治疗,患者可保持完全正常的生活质量。
参考文献
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