|
中国多省市心血管病趋势及决定因素的人群监测 中国MONICA方案 |
| |
Ⅲ.危险因素水平与心血管病的联系
吴兆苏 姚崇华 赵冬 吴桂贤 王薇 刘静 曾哲淳 吴英恺
【摘要】 目的 探讨我国人群心血管病事件发病率和死亡率与危险因素强度和结构之间的联系。方法 对中国MONICA方案10年心血管病监测有关资料进行单因素相关及多因素回归分析。结果 (1)血清胆固醇水平是冠心病事件发病率的显著预测因素，但对冠心病死亡率无明显预测作用；(2)舒张压水平是脑卒中事件发病率和死亡率的显著预测因素；(3)采用多元回归建立的预测模型效果不尽理想；(4)人群危险因素水平趋势与疾病率趋势无显著一致性。结论 中国MONICA方案生态学研究结果较客观地揭示了危险因素水平与心血管病事件率之间的联系，但在探讨前者对后者的预测作用方面有较大局限性。
【关键词】 心血管疾病 监测 MONICA方案
Multiprovincial monitoring of the trends and determinants of cardiovascular diseases(Sino-MONICA project)--III. Association between risk factor levels and cardiovascular disease Wu Zhaosu, Yao Chonghua, Zhao Dong, et al. Beijing Heart, Lung and Blood Vessel Medical Center, Beijing 100029
【Abstract】 Objective To explore the association between disease rate (incidence or mortality) of cardiovascular disease (CVD) events and the intensity and structure of risk factors. Methods Data from the Sino-MONICA study (1984-1993) were analysed using correlation analysis and multivariable regression analysis.Results 1.Serum total cholesterol was a significant predictor for incidence of coronary event, but had no predictive value to mortality of coronary event. 2. Diastolic blood pressure was a significant predictor for both incidence and mortality of stroke event. 3. The prediction of disease rate by risk factor levels using a regression model was unsatisfactory. 4. There was no concordance between trend of risk factors and trend of disease rates. Conclusion Results from ecological study like Sino-MONICA Project can reveal objectively the association between risk factor levels and rates of CVD event , but are less effective in predicting the latter from the former.
【Key words】 cardiovascular disease monitoring MONICA project
中国多省市心血管病人群监测研究采用WHO MONICA方案的方法学和标准在我国十六省市500余万人群中开展对冠心病和脑卒中事件的发病、死亡及危险因素水平长期监测。前文已分别报告十年(1984～1993年)监测结果［1，2］，本文进一步分析疾病率(指发病率或死亡率)与危险因素强度和结构之间的联系及危险因素在心血管病发病和死亡中的作用，并就我国人群心血管病趋势的预测进行初步探讨。
材料和方法
[1] [2] 下一页
上一个医学论文： 经皮球囊二尖瓣扩张术后再狭窄及远期疗效
下一个医学论文： 脂餐后血清甘油三酯代谢异常作为冠心病独立危险因素的探讨
|
|
|
|
|
|
|
您现在的位置： 绿色健康网 >> 医学论文 >> 内科论文 >> 正文