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经皮球囊二尖瓣扩张术后再狭窄及远期疗效 |
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苗来生 戴汝平 崔炜 黄连军 荆宝莲
【摘要】 目的 对经皮二尖瓣球囊扩张术(PBMV)后病人长期随访资料作了回顾性分析，以确定再狭窄率、远期疗效及其影响因素。方法 对1986年5月～1995年12月随访资料完整的160例患者进行了回顾性研究，其中男55例，女105例，年龄38.9±8.9岁。随访时间12～81个月，平均36±15个月。对影响远期疗效的因素，用Cox风险模型作了分析。结果 随访期间，127例(79%)心功能持续改善。超声心动图测得的术前、术后及随访的二尖瓣口面积分别为1.15±0.2cm2、2.15±0.4cm2和1.92±0.4cm2。26例(17%)发生再狭窄，其中17例症状复发。结论 PBMV术后可保持较好的远期疗效，平均36个月的再狭窄率为17%。术前超声心动图计分、心功能、有无心房颤动和左房压为长期疗效的独立预测因素。
【关键词】 二尖瓣狭窄 气囊扩张术 治疗结果
Restenosis and long-term outcome after percutaneous balloon mitral valvuloplasty Miao Laisheng, Dai Ruping, Cui Wei, et al. Department of Radiology, Cardiovascular Institute and Fu Wai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037
【Abstract】 Objective This study reports the clinical follow-up of 160 patients who underwent percutaneous balloon mitral valvuloplasty (PBMV), in order to identify the long-term outcome, the incidence of restenosis, and the determining factors of restenosis. Materials and Methods Eight hundred and thirty one patients with mitral stenosis (MS) underwent PBMV successfully from 1986 through 1995. Among the 831 patients, a retrospective study of 160 cases with complete date was presented in this article. This series included 105 females and 55 males. The mean age was 38.9±8.9 years (15-68 years). They were followed up after the procedure. The data were analyzed with SAS software. Results Follow-up of 12-81 months (median 36±15 months )showed a symptomatic improvement rate of 79% (127 patients) with mitral valve area of 1.92±0.40 cm2. Restenosis was demonstrated in 26 patients (17%).Conclusion PBMV as a treatment for appropriate patients with mitral stenosis has good long-term results.
【Key words】 mitral valve stenosis balloon dilatation treatment outcome
经皮二尖瓣球囊扩张术(PBMV)现已基本替代了二尖瓣闭式分离术。研究表明，其近期疗效满意，但远期疗效尚未充分明了。本文报告我院160例二尖瓣球囊扩张术后病人的长期随访结果，着重研究了国人的再狭窄率、远期疗效及其影响因素。[1] [2] 下一页
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