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电子束CT对冠状动脉钙化的定量研究 |
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张少雄 戴汝平 高润霖 何沙 吕滨 荆宝莲
白桦 姚康宝 陈纪林 杨跃进
【摘要】 目的 探讨冠状动脉钙化与造影所示冠状动脉狭窄间的关系。方法 对218例因临床怀疑或确诊为冠心病而行冠状动脉造影的患者，用电子束CT（EBCT）检查其冠状动脉钙化。结果 冠状动脉狭窄组的钙化总积分明显高于非狭窄组（P<0.001）,二者积分分别为 229±363，42±125。冠状动脉狭窄支数与钙化积分呈正相关。全组冠状动脉钙化预测冠心病的总体敏感性、特异性及准确性分别为82％、75％及79％，与老年组相比，年轻组的特异性较高而敏感性较低。结论 研究结果提示：EBCT钙化积分是预测冠心病的有价值的指标。
【关键词】 冠状动脉疾病 钙质沉着症 体层摄影术，X线计算机
Quantification analysis of coronary artery calcification by electron beam computed tomography in Chinese Zhang Shaoxiong, Dai Ruping, Gao Runlin, et al. Cardiovasclar Institute & Fu Wai Hospital, PUMC & CAMS, Beijing 100037
【Abstract】 Objective To investigate the relationship of coronary artery calcification (CAC) and angiographically significant coronary artery disease. Methods Electron beam computed tomography (EBCT) was performed for detecting coronary calcification in 218 patients underwent coronary angiography whom were suspected coronary artery disease. Significant coronary artery stenosis was defined as greater than 50% narrowing of lumen. Results Among 135 patients in whom CAC was identified, 86% had angiographically significant coronary stenosis, and 82% of 142 patients with angiographically significant coronary stenosis showed CAC by EBCT. The total scores of CAC in patients with significant coronary artery disease (CAD) demonstrated by angiography were much higher than those in patients without CAD, the scores were 229±363, 42±125, respectively (P<0.001). There was a positive relation between the number of vessels with significant stenosis and the total calcification score, on the other hand, the more the vessels with CAC, the higher the probability of the patients with significant coronary stenosis. The overall sensitivity, specificity and accuracy of CAC for stenosis were 82%, 75% and 79% respectively. In the younger age group the sensitivity was lower and the specificity was generally higher than that in the el[1] [2] 下一页
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