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关于核酶治疗病毒性肝炎的研究 |
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Beck J, Michael N. Efficient hammerhead ribozyme-mediated cleav age of the structured HBV en-capsidation signal in vitro & in cell extracts, bu t not in intact cells. Nucl Aci Res, 1995,23:4954-4962.
2，Zu Putlitz J, Yu Q, Burke JM, et al. Combinatorial screening method has been used to identify hairpin ribozymes that inhibit hepatitis B virus (HBV) replicat ion in transfected human hepatocellular carcinoma cell. J Virol, 1999,73:5381-5 387.
3，Welch PJ, Tritz R, Yei S, et al. Intracellular application of hairpin ribozym e genes against hepatitis B virus. Gene Ther, 1997,4:736-743.
4，Welch PJ, Yei S, Barber JR. Ribozyme gene therapy for hepatitis C infection. Clin Diagn Virol, 1998,10:163-171.
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