有较高的通透性，并在HD的基础上增加了对流作用，加强了大中分子的清除，滤器较高的超滤率有利于蛋白质沉积于透析膜表面，而且合成膜具有更多的吸附蛋白作用。HDF对AOPP的清除不仅仅依赖于膜孔径的机械屏障作用，膜的吸附作用可能更为重要，所以对AOPP的清除虽然HDF比HP更有效，但是还不能完全清楚AOPP。
本研究证实常规MHD不能清除AOPP，有文献报道随着时间的推移，AOPP有升高的趋势[9]。因AOPP能加速动脉粥样硬化，所以有条件者采取HDF或者HD+HP取代HD治疗尿毒症将有望减少AOPP积蓄，延缓尿毒症患者心血管并发症的发生。不能进行HDF的单位，间断行血液灌流治疗也不失为一种补救措施。但长期HDF和HD+HP治疗MHD患者的可行性还有待于进一步研究。
【参考文献】
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