本研究中A组患者IC和B组比较有显著增大。结果提示，使用噻托溴胺后患者运动耐力的提高和IC的增加直接相关。
本研究表明，噻托溴胺作为一种新型长效抗胆碱类药物，通过增加IC减少肺的残气容量，临床上可以明显提高COPD患者的运动耐力，改善患者的生活质量。
【参考文献】
[1]KOUMIS T,SAMUEL S.Tiotropium bromide: a new longacting bronchodilator for the treatment of chronic obstructive pulmonary disease[J].Clin Ther,2005,27: 377392.
[2]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南[J].中华结核和呼吸杂志，2002,25:453460.
[3]SIN D D,MCALISTER F A,MAN S F,et al.Contemporary management of chronic obstructive pulmonary disease: scientific review[J].JAMA,2003,290:23012312.
[4]TASHKIN D P,COOPER C B.The role of longacting bronchodilators in the management of stable COPD[J].Chest,2004,125:249259.
[5]van NOORD J A,BANTIJ T A,ELAND M E,et al.A randomised controlled comparison of tiotropium and ipratropium in the treatment of chronic obstructive pulmonary disease[J].Thorax,2000,55:289294.
[6]O’DONNELL D E.Assessment of bronchodilator efficacy in symptomatic COPD: is spirometry useful?[J].Chest,2000,117(2Suppl):42s47s.
[7]PINTOPLATA V M,COTE C,CABRAL H,et al.The 6min walk distance: change over time and value as a predictor of survival in severe COPD[J].Eur Respir J,2004,23:2833.
[8]CELLI B R,MACNEE W,AGUSTI A,et al.Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper[J].Eur Respir J,2004,23,932946.
[9]O’DONNELL D E,Fl GE T,GERKEN F,et al.Effects of tiotropium on lung hyperinflation,dyspnoea and exercise tolerance in COPD[J].Eur Respir J,2004,23:832840.
仁和医学论文网专业提供代写代发医学论文服务，并提供大量论文资料，如有业务需求请咨询网站客服人员!
上一页 [1] [2] [3]
您现在的位置： 绿色健康网 >> 医学论文 >> 内科论文 >> 正文