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急性白血病抗凝纤溶异常的临床意义 |
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.509,P<0.05), compared with the normal control group. However, there is no difference of the markers between the patients in remission stage and the normal control. And the levels of the markers were higher in patients with hemorrhage than in the nonhemorrhage patients (P<0.05). There was no significant differences found between the acute lymphoblastic leukemia group and acute nonlymphocytic leukemia group (P>0.05).Conclusion These results suggest that the function of anticoagulation and fibrinolysis is abnormal in patients with acute leukemia. It’s an important cause of hemorrhage in AL patients and the function would be improved when the patients get better. The levels of AT, AP and PLG are of significant importance for the treating and prognosis in AL.
Key words: Leukemia; Antithrombin; Antiplasmin; Plasminogen
1 对象与方法
1.1 研究对象
正常组：共20例，男12例，女8例，年龄32～68岁。均为我院健康体检者。无心、肝、肾等器质性病变，抽血前2周未服用任何药物。
患者组：共58例，男30例，女28例，年龄3～72岁。均为我院血液科及儿科住院患者，其中急性非淋巴细胞白血病（ANLL）37例其中M210例，M35例，M415例 ,M57例，急性淋巴细胞白血病21例 其中L16例，L215例。白血病诊断参照血液病诊断及疗效标准[1], ANLL M3经全反式维甲酸治疗（剂量为30 mg/d），非M3型通过标准DA方案，ALL通过标准VDP方案治疗，43例曾获得完全缓解（CR），9例复发。对初诊58例，治疗中20例, 缓解期20例，上一页 [1] [2] [3] [4] [5] 下一页
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