|
弥散性血管内凝血患儿凝血障碍的检测及其临床意义 |
| |
【摘要】 目的 探讨弥散性血管内凝血（DIC）患儿凝血障碍的检测及临床意义。方法 用免疫法、发色底物法和凝固法分别测定39例DIC患儿血浆D二聚体（DD）、抗凝血酶活性（AT:A）、凝血酶原时间（PT）、活化部分凝血活酶时间（aPTT）、凝血酶时间（TT）、纤维蛋白原含量（Fbg）等凝血及抗凝指标。结果 DIC患儿的凝血指标与正常对照组儿童间差异有统计学意义，特别是DD含量明显增高，AT:A明显减低，差异具有显著性意义(P<0.01）；DIC发生时死亡组AT:A阳性率达100%。结论 各凝血指标特别是AT:A快速定量检测对DIC的诊断和预后评估有较高价值。
【关键词】 弥散性血管内凝血； 儿童； 凝血； 抗凝 血酶活性
The Measurement of Coagulation in Children with Disseminated Intravascular Coagulation(DIC) and its Significance
YANG Rui，WEI Wenning，YANG Yan，ZHANG Zhiquan,SONG Sanjun.
（Union hospital, Tongji Medical Colledge, Huazhong University of Science and Technology，Wuhan 430022，China）
Abstract: Objective Investigate the measurement of coagulation in children with disseminated intravascular coagulation(DIC) and its significance.Methods Plasm lever of DDimer(DD),antithrombin activity(AT:A),prothrombin time(PT),activated partial thromboplastin time(aPTT),thrombin time(TT) and fibrinogen(Fbg) were tested by immunoological,color substrate and coagulation method.Results The levers of these parameters were significantly different between the DIC children and the normal children. Especially DD increased and AT:A decreased significantly(P<0.01).Sensitivities of AT:A are 100% in patient whom were died of DIC.Concl[1] [2] [3] [4] 下一页
上一个医学论文： 肝素联合华法林治疗脑静脉窦血栓形成12例临床探讨
下一个医学论文： 上肢深静脉血栓形成的临床特征 附14例分析
|
|
|
|
|
|
|
您现在的位置： 绿色健康网 >> 医学论文 >> 内科论文 >> 正文