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冠心病患者血小板参数的变化及其临床意义 |
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【摘要】 目的 研究血小板参数在冠心病(CHD)和急性心肌梗死(AMI)患者中的变化及其临床意义。方法 278例患者分为3组,分别为稳定性心绞痛组(SA)、不稳定性心绞痛(UA)和急性心肌梗死组,非心源性胸痛为对照组。采集所有患者静脉血并用COULTER-750五分类血细胞分析仪检测血小板参数。结果 血小板计数在SA组、UA和AMI组、非心源性胸痛对照组间无明显差别。不稳定性心绞痛和急性心肌梗死组与稳定性心绞痛组和非心源性胸痛对照组相比,血小板平均体积(MPV)和血小板分布宽度(PDW)都明显增大。结 论 血小板体积变大和活化过程可能与冠状动脉血栓形成有关。
【关键词】 血小板;急性心肌梗死;冠心病
Clinical Significance of Platelets Parameters in Patients with Acute Myocardial Infarction and Coronary Heart Disease. ZHU Jie, WU Guo_you, YU Xiao_mei, et al. Zhejiang Hospital, Zhejiang 310013, China.
[Abstract] Objective To explore the changes of platelet parameters in coronary heart disease (CHD) and acute myocardial infarction (AMI). Methods A total of 278 cases were divided into three groups including stable angina group (SA), unstable angina (UA) and acute myocardial infarction group (AMI) and non_cardiac chest pain control group. Venous blood specimens from cases of all groups were analyzed by COULTER-750 automated blood analyzer. Results There was no significant difference in platelet count among non_cardiac pain group and SA, UA and AMI groups. However, mean platelet volume (MPV) in patients with AMI and UA(9.71±1.73 fl) was significantly increased compared with SA group(9.64±0.82 fl) or non_cardiac c[1] [2] [3] 下一页 上一个医学论文: 血浆黏度与纤维蛋白原及血脂的临床相关性多元回归分析 下一个医学论文: d1 3 正丁基苯酞联合阿司匹林治疗脑梗死疗效观察
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