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人工肝治疗重症药物性肝损伤后凝血指标的观察 |
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【摘要】 目的 观察人工肝支持系统治疗重症药物性肝损伤对凝血功能的影响。方法 采用全自动凝血仪分别检测重症药物性肝损伤人工肝治疗前后凝血酶原时间(PT)、凝血酶原时间活动度(PTA)、国际标准化比值(INR)、活化部分凝血活酶时间(aPTT)、纤维蛋白原(Fbg)、D二聚体、凝血因子V、Ⅷ活性。结果 人工肝治疗重症药物性肝损伤后,PT、PTA、INR凝血因子V、Ⅷ活性明显改善,aPTT、Fbg、D二聚体无显著性改变。结论 重症药物性肝损伤患者经人工肝支持系统治疗后,部分凝血功得到改善,病情缓解。
【关键词】 人工肝支持系统; 肝损伤; 药物; 凝血。
Blood Coagulation Changing on the Effects an Artificial Liver Support System in Treating Severe Medicamentous Liver Insufficiency
YANG Xiaojuan, WU Guorong, PEI Hao
(Department of Clinical Laboratory, Hospital of Infectious Disease,Wuxi 214004,China)
Abstract: Objective To study the blood coagulation changing on the effects an artificial liver support system in treating severe medicamentous liver insufficiency. Method Detected prothrombin time (PT), prothrombin time active (PTA ),international normalized ratio (INR) ,activated partial thromboplastin time (aPTT),fibrinogen(Fbg) ,Ddimer and fators V , Ⅷ assay by blood coagulation machine.Results The changing of PT,PTA,INR, fators V and Ⅷ assay has significant difference (P<0.01) .Conclusion Artificial liver support system(ALSS) changed the partly blood coagulation function.
Key words: Artificial liver support [1] [2] [3] 下一页 上一个医学论文: 慢性肝病患者凝血指标和血小板参数的临床应用 下一个医学论文: 妊娠期糖尿病患者血小板参数变化意义的探讨
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