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浅议阿尔茨海默病和血管性痴呆患者血脂的代谢异常 |
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【摘要】 目的 探讨Alzheimer病(AD)和血管性痴呆(VD)患者与血脂代谢异常的关系。 方法 测定了70例AD、50例VD患者血清脂质代谢水平,并与50例非痴呆正常老年人进行比较。 结果 AD组和VD组血浆总胆固醇(TC)、低密度脂蛋白胆固醇(LDLC)明显高于对照组(P<0.05); 高密度脂蛋白胆固醇(HDLC)显著低于对照组(P<0.05)，但AD、VD 2组间差异无统计学意义;VD组三酰甘油(TG)明显高于AD 组及对照组(P<0.05); 载脂蛋白A1和载脂蛋白B各组之间差异无统计学意义。 结论 患者血清TC、LDLC的增高和HDLC的下降可能和痴呆发病有关,调脂治疗可能有助于AD和VD的防治。
【关键词】 阿尔茨海默病; 血管性痴呆; 血脂http:// /
Study of abnormal metabolism of serum lipids in patients with Alzheimers disease and vascular dementia HUANG Aiming,XIE Linzhu,QIN Suping. Department of Geriatrics, Yangzhou Wutaishan Hospital,Yangzhou 225003, China
【Abstract】 Objective To study the relationship between Alzheimers disease (AD) and vascular dementia (VD) patients and the abnormal metabolism of serum lipids. Methods The level of serum lipid in 70 patients with AD,50 patients with VD and 50 normal controls were measured respectively. Results The levels of serum total cholesterol (TC) and LDLC in AD and VD patients were significantly higher than those of normal control group(P<0.05), the level of HDLC in AD and VD groups were significantly decreased compared with the normal control group(P<0.05),but there was no significant difference between AD and VD groups. The level of triglyceride (TG) in VD[1] [2] [3] [4] 下一页
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