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浅议老年原发性高血压患者晨峰现象与靶器官损害 |
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【摘要】 目的 探讨老年原发性高血压晨峰(MBPS)现象对靶器官损害的影响。 方法 老年原发性高血压患者186例，依24 h动态血压分MBPS组(104例)和非MBPS组(82例)。所有对象进行心脏和颈动脉超声检查，计算左室质量指数(LVMI)、颈动脉内膜中层厚度(IMT)及斑块的发生率。 结果 MBPS组24 h、白昼以及夜间平均收缩压、脉压均较非MBPS组高(P<0.05或P<0.01),MBPS组的LVMI及左右两侧颈动脉IMT均明显高于非MBPS组(P<0.05或P<0.01);颈动脉斑块的发生率MBPS组显著高于非MBPS组(P<0.01)。 结论 老年原发性高血压患者具有MBPS现象者有明显的靶器官损害。
【关键词】 高血压晨峰现象; 动态血压监测; 靶器官损害http:// /
Association between morning blood pressure surge and target organ damage in elderly patients with essential hypertension KONG Fanrong. Department of Health Care; GUO Hongmei,DING Xiuping,DING Linfeng. Department of Cardiology, Jiangsu Provincial Official Hospitial, Nanjing 210024,China
【Abstract】 Objective To investigate the association between the morning blood pressure surge (MBPS) and the target organ damage in eldealy patients with essential hypertension. Methods One hundred and eightysix patients were divided into MBPS group (n=104) and nonMBPS group(n=82) according to 24 h ambulatory blood pressure monitoring. Left ventricular mass index (LVMI),carotid intimamedia thickness (IMT) were determined, and the frequency of carotid atherosclerosis and plaque were compared between two groups. Results 24 h,day and night mean systolic blood pressure,pulse pressure in MBPS group were significantly higher [1] [2] [3] [4] 下一页
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