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对老年恶性肿瘤患者合并医院内真菌感染调查 |
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【摘要】 目的 探讨老年恶性肿瘤患者合并医院真菌感染的特点和危险因素,为制定有效的感染防治措施提供依据。 方法 将219例老年恶性肿瘤患者,根据诊断分为真菌感染组和无真菌感染组,回顾性分析2组的一般临床资料及相关指标,先进行单因素比较,然后进行非条件Logistic多元回归分析。 结果 医院获得性真菌感染在肿瘤科发生率为26.94%,主要发生在呼吸道、口腔和肠道。2组单因素比较显示,在伴随基础疾病、年龄、日常活动能力(PS)评分、白细胞减少、抗菌素的使用以及住院时间等方面均存在显著性差异(P<0.05);Logistic多元回归分析表明,住院天数、年龄、PS评分、白细胞减少、抗菌素的使用及合并基础疾病等因素与恶性肿瘤患者医院真菌感染密切相关。推测其是老年恶性肿瘤患者真菌感染的危险因素。 结论 在老年恶性肿瘤患者中,住院天数、年龄、PS评分、白细胞减少、合并基础疾病及抗菌素的使用6个因素可能是老年恶性肿瘤患者合并真菌感染的危险因素,在老年恶性肿瘤患者合并真菌感染的发生发展中起了重要作用。 http:// / 【关键词】 恶性肿瘤; 院内真菌感染; 危险因素
Investigation of hospital fungal infection in elderly patients with malignant tumor ZOU Chunhua,ZHOU Qingchun,FENG Wei,ZENG Qiang,HUANG Taojin,HU Yuanbing. Department of Oncology,Chengdu Hospital of Armed Force, Chengdu 610041, China; TIAN Kun. Department of Respiratory, Chengdu General Hospital of Chengdu Military Command, PLA, Chengdu 610083, China
【Abstract】 Objective To explore the risk factors of hospital acquired fungal infection in elderly patients with malignant tumor. Methods 219 patients with malignant tumor were selected. The data of fiftynine hospital acquired fungal infection cases were investigated. First, single variable analysis was conducted and then multivariate noncondition stepwise Logistic model analysis was conducted. Results The incidence of hospital acquired fungal infection in Department of Oncology was 26.94%. The&nb[1] [2] [3] [4] [5] 下一页 上一个医学论文: 简述线粒体电压依赖阴离子通道对携带线粒体DNA A4263G突变的细胞株线粒体钙循环的影响 下一个医学论文: 浅议吉非替尼治疗老年晚期非小细胞肺癌的临床研究
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