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雷公藤内酯醇洗脱支架抑制小型猪冠脉再狭窄研究 |
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sp;larger than that of bare metal stent group (P<0.05). The neointimal area of the troptolide elutingstent 100 μg group was similar to that of rapamycin elutingstent group (P>0.05), both of which were apparently smaller than the orther three groups(P<0.05). The lumen stenosis rate of the troptolide elutingstent 100 μg group was similar to that of rapamycin elutingstent group (P>0.05), both of which were apparently smaller than the orther three groups(P<0.05). Immunocytochemistry analysis results showed that compare with bare metal stent group, rapamycin elutingstent group , troptolide elutingstent 60 μg and 200 μg group the expression of NFκB protein was less in the troptolide elutingstent 100 μg group (P<0.05); and compare with each other the expression of NFκB protein in the first four groups was no statistic significance.Conclusion Troptolide elutingstent can inhibit the proliferation of intimal, and exhibits a dose dependent effect on preventing instent restenosis within four weeks after the implantation.
Key words： Restenosis; Drug eluting stent; Triptolide
药物涂层支架(drugeluting stent,&nb上一页 [1] [2] [3] [4] [5] [6] [7] [8] 下一页
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