IRS不同因素对心血管疾病危险性的研究。(2)IR/IRS的核心是 糖尿病及心血管疾病危险性，因此，加强临床或社区初级保健中高危人群的筛查，并对其进 行积极有效的干预是降低糖尿病及心血管疾病患病率及病死率的关键。在这方面，大庆地 区已率先作了很好的工作。在有条件的社区也可以根据循证医学/随机对照试验设计进行一 些旨在以心血管事件为临床终点的研究工作。(3)开展IR/IRS筛查/干预的社会卫生经济学分 析。(4)在有条件的医学中心也可进行一些IR/IRS机制的研究，包括胰岛素信号转导网络中I RSs及其下游的若干环节与IR关系的研究以及特异胰岛素、胰岛素原及裂解胰岛素水平与IR 的关系的研究。(5)改善IR的药物，包括对中医中药的开发。参 考 文 献
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