胃癌前病变不同转归中p53 bcl2基因的表达以及细胞增殖活性的研究

　　胃癌前病变的不同转归是一个多因素参与的过程。在本实验中，p53、bcl-2基因表达在其不同转归中差异无显著性，但发生癌变者其增殖活性明显高于尚未发生癌变者；在肠型胃癌，p53、bcl-2癌前阳性者到胃癌时仍全部阳性，与肠型胃癌恶变关系密切。通过监测这些指标有助于早期诊断胃癌。

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