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老年人与青中年急性脑梗塞静脉溶栓治疗的比较 |
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贺建华 张茁 张亮
摘 要：目的 评价老年人急性脑梗塞尿激酶静脉溶栓治疗的有效性和安全性。方法 分析26例急性脑梗塞病人静脉溶栓治疗的临床资料，以60岁为界分为老年组和青中年组进行比较。结果 ①老年组和青中年组均有良好的疗效，有效率依次分别为62.5%和70.0%；②出血合并症在老年组较多，但多数为轻微皮肤出血；③溶栓后再梗塞的机会老年组较多。结论 用尿激酶静脉溶栓治疗老年人急性脑梗塞与青中年患者相比同样有效，也比较安全，但溶栓后再梗塞的机会较多。
关键词：老年人 急性脑梗塞 溶栓治疗
A comparison between the elder and the younger on the thrombolytic
therapy of acute cerebral infarction
He Jianhua
(Department of Neurology, An Zhen Hospital, Beijing 100029)
Zhang Zhuo
(Department of Neurology, An Zhen Hospital, Beijing 100029)
Zhang Liang
(Department of Neurology, An Zhen Hospital, Beijing 100029)
Abstract：Objective To evaluate efficacy and safety of thrombolytic therapy with intravenous urokinase (UK) in acute cerebral infarction (ACI) of the elder patients. Method Twenty-six patients with ACI were studied clinically with CT scan or MRI/MRA before and after thrombolytic therapy with intravenous UK. Of them, sixteen were over sixty years old (60～77) the elder group; ten were below sixty years old (38～58) the younger group. Result (1) The clinical outcome of thrombolytic therapy with intravenous UK were good in both groups, the rate of efficacy was 62.5% in the elder group and 70% in the younger. (2)The edler group seemed to have more hemorrhagic complications, but most of them were mild skin hemorrhage. (3) The chance of reinfaction after treatment was more often in the elder groups. Conclusion The efficacy of thrombolytic therapy with intravenousUK in the elder patients is as good as in the younger, and it seems to be safe too, except for the chance of re-infarction is more in the elder group.
Key words：The elder Acutecerebral infarction Thrombolytic therapy▲
急性脑梗塞的溶栓治疗是当前国内外神经科关注的热点之一，我们以前的报道显示超早期静脉溶栓治疗急性脑梗塞较传统的治疗方法优越［1］。老年人是脑卒中的高危人群，为探讨老年人急性脑梗塞静脉溶栓的安全性、有效性，我们总结我院1995年12月以来收治的溶栓病人，对老年人及青中年进行比较，现报道如下。
资料与方法
一、临床资料
全组病人共26例，以60岁为界分为两组，老年组16例，年龄60～[1] [2] 下一页
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