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复发性脑梗死的危险因素 |
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曾宪武 曾宪平
摘要 为探讨复发性脑梗死(RCI)患者的危险因素及预测指标，检测了46例RCI患者和38例无心脑血管病证据，其他条件基本相同的患者的血糖(GLU)、血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、血浆纤维蛋白原(FG)及血 浆比粘度(RVP比)。结果：RCI患者的GLU呈显著升高(P＜0.01)，HDL-C显著降低(P＜0.05)，而FG呈极显著升高(P＜0.01)，RVP(比)也显著增加(P＜0.05)。提示中老年人有高血压或脑动脉硬化症应定期查GLU、HDL-C、FG及RVP(比)等指标，如发现异常经过及时处理可预防发生脑梗死；而对于已发生过RCI的患者，更应定期查上述各项指标，如发现异常经过及时处理亦可以预防复发性脑梗死。
关键词 脑梗死；复发；危险因素
Investigation on the Risk Factor of Recurrent Cerebral Infarction.
Zeng Xianwu, Zeng Xianping. Department of Neurology, Liyuan Hospital, Tongji Medical University, Wuhan 430077
Abstract In order to study the risk factors and predicting parameters of patients with recurrent cerebral infarction (RCI), 46 patients with RCI and 38 patients without heart cerebral disease as control group were subjected to the determination of GLU, TC, HDL-C, FG and RVP ratio. It was found that the GLU level of the patients with RCI was obviously increased (P＜0.01), HDL-C notably reduced (P＜0.05) as compared with control group, and that FG was very significantly higher (P＜0.001) and RVP ratio markedly increased (P＜0.05). It was concluded that middle-old age patients having hypertension, cerebral arteriosclerosis deserved fix a date to determine GLU, HDL-C, FG and RCP ratio etc. The quick treatment of the disorders was very important for the prevention of cerebral infarction. For the patients having cerebral infarction, regular determination of the above parameters was more important for the prevention of RCI.
Key words recurrent cerebral infarction; risk factor
近年来有关脑梗死的研究颇多，对脑梗死的复发因素的探讨也不少，许多文献提示脑梗死的复发与临床治疗措施有关，也可能与脑血管病的病理生理特征有关［1］。本文旨在探讨预示脑梗死的复发与血浆成分的关系，以指导治疗和预防，为此将46例有CT或MRI证实的复发性脑梗死患者和38例无心脑血管病、其它条件基本相同的患者的血糖(GLU)、总血胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、血浆纤维蛋白原(FG)及血浆比粘度［RVP(比)］的检测结果进行对比研究，探讨其规律，为揭示脑血管病的发病机理及预防复发提供依据。
1 资料与方法
1.1 一般资料 ①研究组：复发性脑梗死患者46例，男41例，女5例；年龄48～86岁，平均69.4±7.1岁。均为我院住院的脑梗死恢复期患者，全部病例符合1995年全国第四届脑血管病的诊断标准。[1] [2] [3] 下一页
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