[摘要] 目的 了解小儿肺炎支原体感染引起传染性单核细胞增多综合征(传单综合征)的临床特征,及时做出诊断和对症治疗,防止误诊。方法 对可疑传单综合征的33例患儿采用ELISA方法检测患儿血清肺炎支原体抗体(MP-IgM)、EB病毒(EBV)、巨细胞包涵体病毒(CMV)、柯萨奇病毒(CVB)、腺病毒(ADV)的特异性抗体(IgM)、乙肝病毒表面抗原,并做嗜异凝集试验。结果 33例MP-IgM≥1∶80,为阳性,应用红霉素治疗14~21天痊愈。 结论 MP感染可致传单综合征,临床症状复杂,可引起多脏器、多系统损害,若及时诊断,应用红霉素治疗预后较好。
[关键词] 肺炎支原体;传染性单核细胞增多综合征
Clinical analysis of 33 cases of infectious monocytosis syndrome caused by infantile pneumonic mycoplasma
LU Yurong.The Pediatric Department of Yibin Second People’s Hospital,Yibin 644000,China
[Abstract] Objective The clinical specialities of infectious monocytosis caused by infantile pneumonic mycoplasma were studied with an aim to make ontime correct diagnosis and proper treatment without amy mistake.Methods 33 cases suspected of infectious monocytosis syndrome were investigated by Elisa’s method.Their blood serum MP-IgM,EBV,CMV,CVB,IgM of ADV and the surface antigen of viral hepatitis type B were all checked.Test of heterophil hemagglutination was also done. Results The MG-IgM of 33 cases were all positive(+)bigger of equal to 1∶80.They were all cured in 14 to 21 days by erythromycine administration. Conclusion Infection due to mycoplasma may lead to infectious monocytosis syndrome.It’s signs and symptoms are rather complicated.It can damage many organs and systems of the patients.An ontime diagnosis and treatment with erythromycine may assure a good prognosis.
[Key words] pneumonic mycoplasma;infectious monocytosis syndrome
近年来,随着国内学者对肺炎支原体(MP)研究的不断深入,证实了MP是小儿急性呼吸道感染的重要病原之一,而且MP感染引起的肺炎多脏器损害也日益被广大医学界同行所认识,有关报道屡见不鲜。本文病例均系重症肺炎支原体感染,均累及2个以上肺外器官,且其临床症状颇似传染性单核细胞增多症,经红霉素治疗痊愈。这类临床症状颇似传染性单核细胞增多症(IM),但非EBV引起的临床综合征称为传染性单核细胞增多综合征[1](简称为传单综合征)[2]。有文献报道病原包括巨细胞包涵体病毒(CMV)、柯萨奇病毒(CVB)、腺病毒(ADV)、肝炎病毒等。现将2000~2005年收治的33例肺炎支
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