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肝素治疗胎儿生长受限临床应用探讨 |
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erine fundus,the length of fetal thigh bone,the head circum and the abdominal circum were obviously increased after treatment with statistical difference(P<0.05).The increase of bipolar diameter(BPD)in standard heparin group was obviously greater than that of the control group(P=0.031).(2)Compared with the result of control group,the ratio of umbilical maximum blood velocity in systolic phase to that of diastolic phase(S/D),pulse index(PI)and resistance index(RI)of the two heparin groups were obviously decreased with statistical difference(P<0.05).However,there is no statistical difference between the two heparin groups(P>0.05).(3)Compared with the control group,fetal age of newborns,birth weight,body length and placenta weight of standard heparin group and LMWH group were obviously increased with statistical difference(P<0.05).However,there is no statistical difference between the two heparin groups(P>0.05).As to the newborn asphyxia,dead fetus in uterus,newborn mortality,preterm birth morbidity and newborn malformation,there was no statistical difference among all groups(P<0.05).In the control group,the incidence of small for dated infant was obviously higher than that of two heparin groups(P=0.005),while there was no statistical difference between the two heparin groups(P>0.05).Compared with the LMWH group,the incidence of transportation to neonatal intensive care unit(NICU)was obviously higher in control group(P=0.003).(4)There was no statistical difference on coagulation function parameters and post partum bleeding morbidity among all groups before and after treatment(P>0.05).Conclusion:Heparin could improve the placenta blood flow and increase the fetal weight.It decreases the incidence of small for dated infant and does not increase the incidence of post partum bleeding.The incidence of transportation to NICU was obviously lower in the LMWH group than that of control group.LMWH is more effective and convenient than standard heparin and 上一页 [1] [2] [3] [4] [5] 下一页
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