有显著差异。而宋亭等人认为正常脊髓C2-3水平最高,越往尾侧FA值越低,颈髓四个节段ADC值没有明显差别。管红梅等人则认为正常颈髓C1水平FA值低于颈髓C2-7水平。实验表明,脊髓慢性压迫损伤造成脊髓ADC值增大,以横向ADC值增大为主,FA值降低。但是也有不同的实验结果,有实验发现FA值在脊髓慢性损伤中增高,而ADC值没有变化;有1例脊髓慢性损伤患者ADC值和FA值均增高;脊髓压迫部位FA值呈现动态变化;随着症状持续时间的延长而FA值逐渐下降。对于ADC值和FA值变化的程度能否反应出脊髓损伤的严重程度目前还没有明确的结论。本研究结果中, 急性期脊髓损伤后的ADC 值与损伤前比较(0.97±0.181) ×10 -3 mm2/s,(1.16±0.16)×10 -3 mm2/s, ADC 值升高差异无显著性差异(t=1.676, P =0.07); FA 值与损伤前比较0.58±0.10,0.34±0.06,FA 值降低差异有显著性意义(t =4.512 , P =0.002),提示DTI 能对实验性脊髓急性期损伤后的观察提供有价值的信息。
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