|
无症状儿童人群中幽门螺杆菌感染的血清流行病学 |
| |
许春娣 周建元 薛英 奚容平 苏林 陈舜年 徐家裕
【摘要】 目的 了解我国无症状儿童人群中幽门螺杆菌(Hp)感染率，探讨社会经济条件等因素对Hp流行的影响。方法 采用Bio-Rad GAP IgG药盒，ELISA方法检测1 119位7～14岁健康学生血清中Hp-IgG抗体。结果 儿童Hp平均感染率为40.93%，居住农村者为49.83%，居住市区者为31.49%。7岁组为30.91%，8岁为34.93%，9岁为38.92%，10岁为46.11%，11岁为48.67%，12岁为47.30%；此外，发现儿童Hp感染率工人家庭为47.93%，农民家庭为43.90%，职员家庭为32.74%，其他为30.43%。结论 我国无症状儿童人群中Hp感染率较高，并随着年龄递增，与社会经济地位、文化卫生水平呈反比关系。
【关键词】 螺杆菌，幽门 流行病学 儿童 螺杆菌感染
Seroepidemiology of Helicobacter pylori infection among asymptomatic children XU Chundi*, ZHOU Jianyuan, XUE Ying, et al.* Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025
【Abstract】 Objective To investigate the prevalence of Helicobacter pylori (Hp) infection among asymptomatic Chinese children and possible relationship between the socioeconomic status of their families and the prevalence.Method Serum Hp-IgG antibodies of 1 119 school children 7 - 14 years of age were measured by ELISA method with Bio-Rad GAP IgG Kit.Results Mean prevalence of Hp infection was 40.93% ; the pre-valence was 49.83% in rural area and 31.49% in urban area. The prevalences of Hp infection among different age groups were as follows: 7 year, 30.91%, 8 year, 34.93%; 9 year, 38.92%; 10 year, 46.11%; 11 year, 48.67%; 12 year, 47.30%. Besides, the authors found that Hp infection rate of children was 47.93% in worker′s families, 43.90% in peasants′ families, 32.74% in professionals families, 30.43% in others.Conclusion Prevalence of Hp infection among in the population studied was high and it incerased with age. There was an inverse correlation between the infection rate and the level of socioeconomic status.
【Key words】 Helicobacter pylori Epidemiology Child Helicobacter infections
幽门螺杆菌（Helicobacter pylori，Hp），因其与慢性活动性胃炎、十二指肠溃疡的发生密切相关，与胃腺癌也有关联，而受到广泛关注［1，2］。我们曾用血清学方法对部分患有胃十二指肠疾病的儿童作过Hp感染的调查，结果8岁组为57.48%，12岁组达66.36%［3］，反映了有消化道症状儿童人群中Hp感染率是相当高的，且与胃十二指肠疾病有关。但在无消化道症状健康儿童人群中Hp的感染率是多少，影响Hp传播的因素及与社会经济地位的关[1] [2] [3] 下一页
上一个医学论文： 抗生素对小儿呼气氢试验的影响
下一个医学论文： 肺炎链球菌对抗生素耐药性的研究
|
|
|
|
|
|
|
您现在的位置： 绿色健康网 >> 医学论文 >> 妇产科论文 >> 正文