|
沙眼衣原体感染输卵管性不孕患者输卵管液中肿瘤坏死因子 和白细胞介素6的测定 |
| |
李海燕 梁占光
【摘要】 目的 探讨沙眼衣原体（CT）感染所致输卵管性不孕患者输卵管液中肿瘤坏死因子α（TNF-α）和白细胞介素6（IL-6）的水平及其意义。方法 用酶联免疫吸附试验法测定22例CT感染输卵管性不孕（A组）、23例非CT感染输卵管性不孕（B组）及19例已生育输卵管正常妇女（对照组）输卵管液中TNF- α和IL-6 的水平。结果 A 组TNF-α的水平为178 ng/L，高于对照组的124 ng/L（P<0.01）；A组中输卵管阻塞者TNF-α为199 ng/L，高于粘连者的142 ng/L（P<0.01）。A 组IL-6的水平为681 ng/L，高于B组的264 ng/L及对照组的229 ng/L（P均<0.01），B组与对照组之间比较差异无显著性（P>0.05）。结论 无症状输卵管CT感染可使输卵管液中TNF-α和IL-6升高，其中TNF-α与输卵管损伤程度有关。TNF-α越高，损伤越重。
【关键词】 衣原体，沙眼； 输卵管疾病； 不育，女(雌)性;肿瘤坏死因子; 白细胞介素6
Determination of Tumor Necrosis Factor-alpha and Interleukin-6 Levels of the Tubal Fluids in Patients with Infertility Caused by Infection of Chlamydia Trachomatis
LI Haiyan, LIANG Zhanguang.
（Department of Obstetrics and Gynecology，Dali Medical College，Dali 671000, Yunnan Province, China）
【Abstract】 Objective To study the levels of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) in tubal fluids of tubal factor infertile (TFI) women due to chlamydia trachomatis (CT) infection and its implication. Methods Twenty-two TFI women with CT infection (group A), twenty-three TFI women without CT infection (group B) and nineteen fertile women with normal tubes (group control) were enrolled for study. Levels of TNF-α and IL-6 in tubal fluids were measured by enzyme-linked immunosorbent assay. Results Group A had significantly higher TNF-α levels than those of group control (178 ng/L versus 124 ng/L, P<0.01). Moreover, women with tubal blocks had significantly higher TNF-α than those of tubal adhesions (199 ng/L versus 142 ng/L, P<0.01). IL-6 levels of group A were significantly higher than those of group B and group control (681 ng/L versus 264 ng/L and 229 ng/L, both P<0.01),but there is no difference between group B and group control. Conclusions Local TNF-α and IL-6 levels increased in silent tubal infection of CT. TNF-α had a po[1] [2] [3] 下一页
上一个医学论文： 雌激素对去势兔血脂 内皮素及动脉粥样硬化形成的影响
下一个医学论文： 近10年异位妊娠诊断及治疗的变化 附1 970例分析
|
|
|
|
|
|
|
您现在的位置： 绿色健康网 >> 医学论文 >> 妇产科论文 >> 正文