环氧合酶 2和ki 67在宫颈鳞状细胞癌组织中的表达

　　COX-2蛋白表达增高可能是细胞生物学行为改变的早期事件。COX-2通过调节宫颈局部免疫，影响细胞增殖，促进一个更利于细胞恶变的环境产生，促使宫颈由慢性宫颈炎向CIN和SCC转变。COX-2在宫颈癌早期发生阶段起着重要作用，这为预防宫颈癌提供了新的思路。

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