【摘要】 目的:对比组织间碘-125粒子植入放射治疗和铱-192近距离后装放射治疗的两种方法,探讨不同方法治疗后患者的健康恢复情况和性生活质量问题。方法:采用两种放射治疗方法,即碘125粒子组织间永久植入放射治疗和铱-192近距离后装放射治疗。后装组(40例)是在进行宫颈癌广泛子宫切除术后采用铱-192近距离后装放射治疗,每周1次,每次常规剂量600~800 cGy,以A点为剂量参照点,一般6~8次,后装放射一般从第1~2周开始。粒子组(43例)是在手术结束关腹前将粒子植入盆腔指定位置,入选后装组或粒子组是根据患者的经济状况和意向决定的。结果:治疗6个月后血清性激素水平粒子组FSH、LH的平均值明显高于后装组,差异具有统计学意义(P﹤0.05)。治疗6个月后进行性问题问卷调查显示:愉快程度、性欲、阴道情况等问题都显示粒子组与后装组治疗效果有可比性(P﹤0.05)。结论:碘-125放射性粒子植入术治疗早、中期宫颈癌具有安全有效、创伤小、并发症少、近期疗效显著、提高性生活质量等优点。
【关键词】 宫颈癌;放射治疗;性生活质量
Survey about the affection of sex life in young cervical cancer patients with radiation-surgery GENG Jin-ping, AN Li-bin, LI Wen-tao (Nursing College of Jilin University, Changchun 130021, China)
Abstract:ObjectiveComparison between the organization of Iodine-125 implantation of radioactive treatment and Iridium-192 close range afterloading radiation therapy,to explore patients′ post-recovery health and quality of sex life after different methods of treatment.MethodTaking two methods,the organization of Iodine-125 implantation of radioactive treatment and Iridium-192 close range afterloading radiation therapy,group of Iridium-192(n=40) took the Iridium-192 close range afterloading radiation therapy after cervical cancer radical hysterectomy,once a week,600~800 cGy each time,refering to A as reference,6~8 times.Group of Iodine-125(n=43) implanted the particle to the specified location in intraperitoneal before operation ending.ResultsAfter 6 months′ treatment,the average level of FSH,LH of group Iodine-125 was higher than group of Iridium-192,the difference was significant (P<0.05).The survey of sex life after 6 months′ treatment showed that the degree of pleasure,sexual desire,vaginal situation and other issues in the group Iodine-125 were more effective than group of Iridium-192(P<0.05).ConclusionThe organization of Iodine-125 implantation of radioactive treatment has the advantages of safe,less trauma,less complications,signif
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