【摘要】 目的: 探讨宫颈肿瘤筛查中液基细胞学检查(TCT)、阴道镜下活检联合应用的临床价值。方法：收集200212~200510月间张家口市及周边地区9250例已婚妇女进行常规细胞学检查，可疑宫颈病变3536例患者行液基细胞学检查，阴道镜检查及病理组织学检查。结果：液基细胞学筛查检出阳性涂片212例，占822%(212/258)，其中不典型鳞状上皮细胞(ASCUS)占151%(32/212)，鳞状上皮内低度病变(LAIL)占656%(144/212);鳞状上皮内高度病变(HSIL)占798%(14/16)，鳞状细胞癌(SCC)占100%(22/22)。阴道镜检查阳性例数为242例，占总数的938%(242/258);经病理确诊为CIN及浸润癌者共197例，占TCT异常者929%(197/212)，占阴道镜异常图象816%(197/242)。年龄分布上，以28~35岁发病者所占比例最大(485%)。结论：在宫颈病变的早期筛查中TCT联合阴道镜下活检具有重要的临床意义。
【关键词】 细胞学检查; 宫颈病变; 筛查;TCT
The Significance of TCT、Uterine Electron Microscope in Cervical Carcinoma Screening
CHEN Jiangping1, SHU Lisha1, ZHANG Fan2, et al
1.Department of Obstetrics and Gynecology， The First Affiliated Hospital, Hebei
North University,Zhangjiakou， 075000, Hebei, China;2.Department of Pathology,
The First Affiliated Hospital, Hebei North University,Zhanjiakou,075000,Hebei, China
【ABSTRACT】 Objective: To investigate the clinical Significance of TCT and uterine electron microscope in the cervical carcinoma screening. Methods: From Nov2002 to Oct2005,9250 cases in Zhangjiakou and its area were carried cervical scraping smear, and 3536 cases with questionable cervical carcinoma were checked by TCT、uterine electron microscope and pathologic biopsy. Results: The positive rate of TCT was 822%,and the rates of ASCUS, LAIL HSIL,SCC were listed respectively as follows: 151%,655%,798%,100%. The positive rate of the uterine abnormity image was 938%;197 cases were diagnosed CIN and invasive cervical carcinoma,occupying 929% (197/212) of abnormal TCT and 816% (197/242) of the uterine electron microscope abnormity image. For ages, patients between 28~35 years had high incidence of early cervical cancer(485%).Conclusion: There is a vital clinical significance for TCT and the uterine electron microscope in detecting the early cervical carcinoma screening.
【KEY WORDS】 Cervical scraping smear; Cervical carcinoma; Screening; TCT
宫颈病变是妇科常见疾病，近
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