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罗氏内异方联合腹腔镜手术对轻型子宫内膜异位症不孕患者血清MMP 9 TIMP 1的影响

B-US and give a good guide for sex time for both group patients.ELISA is applied to t...更多est the level of serum MMP-9 and TIMP-1 and to calculate the ratio of both factors before and three months after Laparoscopic surgery.Observe the symptom improvement and the statistical efficiency of the two groups three months after treatment.Calculate the pregnancy rate,abortion rate,after 6 months follow-up.Results(1) Chinese herbal medicine combined laparoscopic surgery group is obviously superior to simple laparoscopic surgery in improving dysmenorrhea,anal expansion,sexual intercourse pain and lower abdominal pain (P<0.05),and it has no significant difference in improving lumbosacral discomfort between both groups(P>0.05).(2) Pregnancy rate in patients of Chinese herbal medicine combined laparoscopic surgery group was 70%(14/20),significantly higher than 31.6%(6/19) of simple operation group (P<0.05).Abortion rate of Chinese herbal medicine combined laparoscopic surgery group was 7.1%(1/14),lower than simple operation group which abortion rate is 33.3%s,no significant difference in contrast of both group (P>0.05).(3) Levels of serum MMP-9,MMP-9/TIMP-1 in the two groups after treatment were significantly lower before treatment,and the difference was significant(P<0.05).These levels in Chinese herbal medicine combined operation group were significantly lower(P<0.05) than simple operation group after treatment.After treatment,levels of serum TIMP-1 in the two groups were significantly higher than before treatment(P<0.05).And they were significantly higher in Chinese herbal medicine combined operation group than imple operation group,the difference was significant(P<0.05).Conclusion 1.Luoshineiyifang combined laparoscopic is a effective way to treat the patients of mild Endometriosis associated intertility.It can significantly improve the main clinical symptoms,and improve the pregnancy rate.2.The mechanism of Luoshineiyifang combined with laparoscopic surgery treated the mi

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