腹腔镜胆囊切除术围手术期抗生素应用价值的探讨

【摘要】  目的：探讨腹腔镜胆囊切除术（ＬＣ）围手术期抗生素应用的价值。方法：随机将择期行ＬＣ的１ ００９例患者分为３组：Ａ组，手术前后均不使用抗生素；Ｂ组，手术当天使用１次抗生素；Ｃ组，术后连续３d使用抗生素。结果：ＬＣ术后切口、腹部、肺部感染发生率，Ａ、Ｂ、Ｃ各组之间差异无统计学意义，但术中切口、腹腔污染及手术时间差异有统计学意义。结论：择期ＬＣ围手术期使用抗生素不能进一步降低术后切口、腹腔、肺部感染的发生率，但可减少切口和腹腔的污染，缩短手术时间。

　　【关键词】  胆囊切除术，腹腔镜；抗生素类；围手术期；感染控制

　　The value of using antibiotic in peroperative period of laparoscopic cholecystectomy

　　FANG Zhiheng,HOU Yafeng,WU Wei.

　　The People s Hospital of Tongling City,Tongling 244000,China

　　【Abstract】  Ｏbjective:To explore the value of using antibiotic in peroperative period of laparoscopic cholecystectomy(LC).Methods:1 009 patients who were chosen an auspicious day to be performed LC were divided into 3 groups randomly:A group,antibiotic had not been used preand postoperation;B group,antibiotic had been used once on the operative day;C group,antibiotic had been used for 3 days continuously after operation.Results:There was no significant difference among A,B,C group in the terms of the incision,abdominal and pulmonic infection incidence rate,but there was significant difference in terms of the pollution rate of incision and abdominal cavity and the operation time.Conclusions:The use of antibiotic in peroperative period of LC can t decrease the incidence rate of the incision,abdominal and pulmonic infection;but the antibiotis can decrease the pollution of incision and abdominal cavity,shorten the operative time.

　　【Key words】  Cholecystectomy,laparoscopy;Antibiotics;Peroperative periad;Infection control

    临床上滥用抗生素不仅增加患者的治疗费用，而且导致大量耐药菌株出现，给临床工作带来困难。为探讨腹腔镜胆囊切除术（LC）围手术期抗生素应用的价值，１９９６年１月至２００５年５月我们选择择期ＬＣ患者进行前瞻性随机对照研

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