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脑转移瘤外科诊治探讨

摘要】 

    目的  探讨脑转移瘤手术指征、术后放疗或化疗与预后之间的关系,为脑转移瘤的治疗提供科学的依据,以延长患者寿命。

  方法  回顾性分析脑转移瘤217例的临床资料。

  结果  行手术治疗的207例病人中,随访157例,术后存活半年以内者118例,存活率75.2%;术后125例行放疗,平均生存期10个月,32例术后行放疗+化疗,平均生存期13个月(P<0.01,χ2检验)。未手术治疗及放、化疗的10例自确诊到死亡为22~60天(P<0.01,χ2检验)。

  结论  脑转移瘤手术较未手术生存时间长,采用手术、放疗、化疗等综合治疗手段,是行之有效的,只要患者一般情况好,经济条件允许,应予积极治疗。

  【关键词】  脑转移瘤;诊断;外科治疗

  The investigation of surgical treatment to intracranial metastatic tumors:clinical analysis of 217 cases

   【Abstract】 

    Objective  To evaluate the relationship among the indication of neurosurgery,post-operation radiotherapy or post-operation chemotherapy to intracranial metastatic tumors.

  Methods  A retrospective statistic study was performed after all (217 cases) clinical information transformed into qualitative data.

  Results  157 cases were followed-up,among them 118 cases survived within 6 months.Among 125 cases,the average life span was 10 months after operation

   radiotherapy.Among 32 cases,the average life span was 13 months after operation

   radiotherapy

   chemotherapy.(P<0.01).10 cases died within 22~60 days without operation after diagnosed.(P<0.01).

  Conclusion  Neurosurgical operation combined with stereotactic radiotherapy and chemotherapy are the effective treatment method to intracranial metastatic tumors.

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